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the cattle near puberty (12-15 months), and the incubation period of the disease is 5 or more years. The period of actual infection to death is frighteningly brief; the animal is usually dead within 4 months of showing symptoms. BSE belongs to a group of animal diseases term Transmissible Spongiform Encephalopathy (TSE). Different forms of TSE diseases can affect felines, rodents, and other ruminant animals. The microorganism responsible for BSE and TSE’s is smaller than the smallest viruses. This microorganism is called a prion